Keep in mind that this is the Catalyst 12.5 Beta, which means that some things may not necessarily work very well. Then again, the build is supposed to only come out in late May, 2012. Only the Windows Vista/7-compatible version of the driver is available (both 32 and 64-bit).
That said, we aren't going to recommend that people just go ahead and get this early Catalyst leak. That isn't to say we've had problems. We haven't actually tested it after all.
Then again, people around the net have taken the risk, and some of them say that they like them so far. For example, one said that the FSAA settings have been rearranged and that MLAA use in games doesn't cause Aero to lag (12.4 WHQL is said to seriously suffer from this), among other things.
That said, if you don't feel like the 12.5 is a safe bet, there is always the 12.4 release. We have a discussion thread open over here.